Table 1.

Physiological parameters during brain ischemia and hemorrhagic transformation (HT) and mortality within 72 h after brain ischemia

	Temperature (°C)	Heart rate (beats/min)	Blood glucose (mg/dl)	HT rate (%)	Mortality (%)
Two bolus experiments
Saline	37.0 ± 0.1	475 ± 22	232 ± 32	70	40
TSC 0.14 mg/kg	37.1 ± 0.1	460 ± 16	263 ± 37	62.5	0
TSC 0.28 mg/kg	37.1 ± 0.1	465 ± 11	266 ± 78	71.4	0
TSC 0.70 mg/kg	37.2 ± 0.1	462 ± 37	249 ± 46	85.7	14
Bolus-infusion-bolus experiment
Saline	37.2 ± 0.0	462 ± 12	255 ± 27	86.7	60
TSC 0.14 mg/kg	37.1 ± 0.0	464 ± 10	211 ± 31	43.8*	25

The temperature, heart rate and blood glucose data were obtained at the time when the middle cerebral arterial occlusion was achieved. Results are mean ± S.E.M. (n = 7 – 16).

^*P < 0.05 compared with the corresponding saline group.