TABLE 2.
Postoperative morbidity of CRS/HIPEC procedures (n = 1,019)
| Variable | Time interval (days) | Non-DP (n = 956) | DP (n = 63) | p value |
|---|---|---|---|---|
| Minor morbiditya [n (%)] | 30 | 166 (17.4) | 12 (19.1) | 0.732 |
| 31–90 | 50 (5.2) | 4 (6.4) | 0.5702 | |
| Major morbidityb [n (%)] | 30 | 180 (18.8) | 19 (30.2) | 0.033 |
| 31–90 | 58 (6.1) | 5 (7.9) | 0.584 | |
| Mortality [n (%)] | 30 | 23 (2.6) | 2 (3.2) | 0.79 |
| 31–90 | 16 (1.8) | 1 (1.6) | 1.00 | |
| Readmission [n (%)] | 30 | 166 (21.1) | 14 (29.2) | 0.205 |
| 31–90 | 243 (31.9) | 18 (33.3) | 0.881 | |
| Operation time [h; mean (SD)] | 8.4 (3.1) | 10.2 (3.2) | <0.0001 | |
| Hospitalization [days; mean (SD)] | 14 (16) | 22 (28) | <0.001 | |
| ICU stay [days; mean (SD)] | 3.5 (9.4) | 4.6 (7.9) | 0.007 | |
| Estimated blood loss [ml; mean (SD)] | 760 (775) | 1,172 (701) | <0.001 | |
CRS/HIPEC cytoreductive surgery with intraperitoneal hyperthermic chemotherapy, DP distal pancreatectomy, ICU intensive care unit, SD standard deviation
Clavien and Dindo Grade I–II
Clavien and Dindo Grade III–IV