Table 1. Biodistribution study in SKBR-3 tumor-bearing nude mice at 4, 24 and 48 h postinjection of [¹¹¹In]-DTPA-trastuzumab-IRDye 800. Values are expressed as x̄±s %ID/g in groups of three to four animals for each time point.

Tissue	Percentage of injected dose per gram (x̄±s, %ID/g)
Tissue	4 h	24 h	24 h blocked*	48 h
Blood	12.40±2.68	2.34±0.17	2.28±0.41	0.78±0.27
Liver	10.74±2.05	7.79±1.71	7.23±0.32	7.41±1.24
Kidney	15.38±3.28	19.37±1.22	17.60±2.22	15.63±1.28
Stomach	2.38±0.42	2.84±0.74	2.65±0.57	2.77±0.46
Brain	0.60±0.27	0.46±0.29	0.45±0.34	0.39±0.18
Muscle	1.83±0.94	1.38±0.24	1.31±0.86	0.81±0.33
Bone	4.62±0.71	4.26±0.71	3.28±2.12	2.91±0.51
Tumor	8.78±1.80	12.42±1.72	2.78±0.66	9.96±1.05

*, blocked with 50 μg trastuzumab.

Table 1. Biodistribution study in SKBR-3 tumor-bearing nude mice at 4, 24 and 48 h postinjection of [111In]-DTPA-trastuzumab-IRDye 800. Values are expressed as x̄±s %ID/g in groups of three to four animals for each time point.