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. 2015 Feb 7;12:24. doi: 10.1186/s12974-014-0232-1

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© Walter et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effect of AMD3100 treatment on infarct size and accumulation of green fluorescent protein (GFP)-positive cells in the ischemic territory. (A) Infarct volumes in mice treated with saline (n = 9) or AMD3100 (n = 9) displayed as means ± SEM on day 14 after photothrombosis. Representative coronal sections of a vehicle- and AMD3100-treated animal are shown to the right. (B) Accumulation of GFP⁺ cells in the ischemic territory in a vehicle- and an AMD3100-treated CX₃CR1^+/GFP mouse. Scale bars: 200 μm. The frame illustrates the area analyzed for GFP⁺ cells by 2-photon-laser-microscopy.