Table 1.

Composite neuroscore for quantification of neurological deficits before and after photothrombotic stroke at days 1, 2, 7 and 14

Test	Score and description
Left forelimb flexion in suspension	0 - impaired paw is not moving and tightly held to the trunk
	1 - impaired paw mostly held to the trunk, slightly movable
	2 - impaired paw moves up and down, asymmetry to other paw
	3 - slight asymmetry between the paws, both paws well movable
	4 - normal, symmetric
Paw placement of the left side	0 - paw totally immobilized, hanging down, no movement
	1 - paw hanging, but little movement back and forth (horizontal plane)
	2 - paw hanging, horizontal and vertical movement below table level
	3 - paw hanging horizontal and vertical movement up to table surface level
	4 - paw hanging, mobile in all directions, reaching the table surface
	5 - normal, paw is immediately taken up to the table surface
Whisker-reflex, left side	0 - not present
	2 - present
Faults of the left forelimb walking 27 steps on a grid, 46.5 cm long, step size 2 mm, interspace 1.5 cm (2–3 training sessions)	0 - 6 faults or more
	1 - 5 faults
	2 - 4 faults
	3 - 3 faults
	4 - 2 faults
	5 - 1 fault
	6 - no fault step

Before photothrombosis, the animal should achieve 22 points, at day 1 < 11 points, otherwise the animal was excluded from the study.