Table 1.

Renal functional parameters in the study groups (mean ± SD)

	NDCM (n = 8)	D (n = 8)	DR (n = 8)	DCM (n = 8)	DRCM (n = 8)
Serum creatinine (mg/dl)	0.56 ± 0.05#	0.36 ± 0.03	0.38 ± 0.03	0.89 ± 0.06*	0.42 ± 0.04+
Serum BUN (mg/dl)	14.98 ± 1.62	15.23 ± 1.32	16.26 ± 1.48	16.38 ± 1.93	16.45 ± 1.53
Creatinine clearance (ml/min)	1.53 ± 0.18#	2.68 ± 0.25	2.59 ± 0.24	1.08 ± 0.09*	1.98 ± 0.22+
FENa (%)	0.32 ± 0.15	0.29 ± 0.10	0.28 ± 0.09	0.31 ± 0.14	0.33 ± 0.13
Urine microprotein (mg/dl)	70.2 ± 22.1#	45.2 ± 11.3	38.6 ± 14.3	108.5 ± 23.4*	69.3 ± 18.2#

NDCM: non-diabetic rats + contrast media, D: diabetic group, DCM: diabetic rats treat + contrast media, DR: diabetic rats + rosuvastatin, DRCM: diabetic rats + rosuvastatin + contrast media.

*P < 0.01 vs NDCM, D, D R and DRCM; + P < 0.05 vs NDCM, D and DR, # P < 0.05 vs D, DR.