Table 4.

Estimated odds ratios between dry eye disease and each of depression, anxiety and rheumatoid arthritis, by age group.

Disease Age group	Adjusted Odds Ratio*	95% Confidence Interval	P-Value†
Anxiety			0.001
18 to 35	2.4	(1.8, 3.1)
36 to 50	2.0	(1.7, 2.4)
51 to 65	3.0	(2.6, 3.4)
> 65	3.1	(2.7, 3.5)
Depression			0.004
18 to 35	2.1	(1.7, 2.7)
36 to 50	2.5	(2.2, 2.9)
51 to 65	3.1	(2.8, 3.5)
> 65	3.1	(2.8, 3.4)
Rheumatoid Arthritis			0.003
18 to 35	6.8	(3.6, 12.8)
36 to 50	3.7	(2.6, 5.2)
51 to 65	3.8	(3.1, 4.6)
> 65	2.5	(2.0, 3.1)

^*Adjusted for patient gender.

^†P-value from test of interaction between disease and age group.