Table 1.
Reperfusion | ||||||
---|---|---|---|---|---|---|
Baseline | Occlusion | 3 min | 1 h | 2 h | 3 h | |
HR (min−1) | ||||||
control | 253 ± 35 | 246 ± 40 | 229 ± 26 | 225 ± 28 | 221 ± 29 | 212 ± 31 |
NIR5x | 264 ± 37 | 245 ± 10 | 240 ± 23 | 235 ± 21 | 230 ± 25 | 221 ± 21 |
NIR3x | 244 ± 31 | 204 ± 15 | 209 ± 15 | 208 ± 20 | 204 ± 22 | 189 ± 10 |
.4Nitr | 253 ± 29 | 250 ± 24 | 234 ± 20 | 237 ± 19 | 222 ± 19 | 227 ± 23 |
4.0Nitr | 260 ± 25 | 245 ± 20 | 238 ± 17 | 233 ± 16 | 222 ± 12 | 218 ± 16 |
.4Nitr+NIR3x | 248 ± 29 | 217 ± 29 | 219 ± 28 | 212 ± 32 | 203 ± 22 | 198 ± 22 |
3mWRad-Post | 253 ± 21 | 233 ± 21 | 220 ± 12 | 221 ± 15 | 209 ± 12 | 201 ± 11 |
60mWRad-Post | 241 ± 13 | 222 ± 18 | 210 ± 18 | 206 ± 21 | 199 ± 17 | 196 ± 18 |
3mWRad-Post+.4Nitr | 244 ± 27 | 219 ± 23 | 214 ± 25 | 214 ± 26 | 206 ± 30 | 201 ± 31 |
MAP (mmHg) | ||||||
control | 74 ± 10 | 58 ± 9 | 57 ± 6 | 60 ± 9 | 61 ± 11 | 59 ± 10 |
NIR5x | 74 ± 14 | 55 ± 8 | 67 ± 10 | 68 ± 12 | 66 ± 7 | 66 ± 7 |
NIR3x | 76 ± 8 | 56 ± 11 | 59 ± 11 | 63 ± 7 | 58 ± 7 | 64 ± 9 |
.4Nitr | 69 ± 15 | 61 ± 12 | 60 ± 9 | 59 ± 9 | 60 ± 9 | 60 ± 9 |
4.0Nitr | 77 ± 13 | 60 ± 10 | 59 ± 11 | 55 ± 7 | 59 ± 12 | 62 ± 12 |
.4Nitr+NIR3x | 73 ± 9 | 55 ± 9 | 58 ± 9 | 57 ± 8 | 58 ± 6 | 59 ± 4 |
3mWRad-Post | 67 ± 6 | 64 ± 2 | 64 ± 5 | 67 ± 4 | 66 ± 5 | 67 ± 6 |
60mWRad-Post | 71 ± 9 | 64 ± 10 | 65 ± 11 | 63 ± 9 | 61 ± 10 | 63 ± 11 |
3mWRad-Post+.4Nitr | 69 ± 6 | 55 ± 7 | 56 ± 9 | 59 ± 7 | 58 ± 9 | 59 ± 5 |
RPP (min−1•mmHg•10−3) | ||||||
control | 21.2 ± 4.3 | 16.7 ± 3.9 | 15.4 ± 2.3 | 15.7 ± 2.4 | 16.0 ± 3.6 | 14.6 ± 3.5 |
NIR5x | 22.1 ± 4.3 | 15.7 ± 2.1 | 18.4 ± 3.2 | 18.5 ± 3.8 | 17.6 ± 2.9 | 16.9 ± 2.5 |
NIR3x | 21.0 ± 3.5 | 13.4 ± 1.8 | 14.3 ± 2.7 | 15.1 ± 1.5 | 13.6 ± 1.4 | 13.8 ± 1.9 |
.4Nitr | 20.4 ± 6.1 | 17.7 ± 4.8 | 16.4 ± 2.4 | 16.2 ± 2.8 | 15.6 ± 2.7 | 15.7 ± 2.7 |
4.0Nitr | 22.5 ± 3.8 | 17.2 ± 3.4 | 16.5 ± 3.1 | 15.1 ± 0.9 | 15.3 ± 2.6 | 15.5 ± 2.3 |
.4Nitr+NIR3x | 20.6 ± 3.2 | 14.3 ± 2.8 | 15.0 ± 2.7 | 14.4 ± 3.1 | 13.7 ± 1.4 | 13.6 ± 1.1 |
3mWRad-Post | 19.5 ± 2.4 | 16.9 ± 1.6 | 16.2 ± 1.8 | 17.0 ± 1.6 | 15.9 ± 1.7 | 15.5 ± 1.6 |
60mWRad-Post | 19.5 ± 2.8 | 16.5 ± 3.0 | 15.8 ± 3.2 | 15.3 ± 3.3 | 14.3 ± 2.9 | 14.2 ± 3.0 |
3mWRad-Post+.4Nitr | 19.2 ± 2.8 | 14.3 ± 2.5 | 14.1 ± 2.7 | 14.7 ± 2.7 | 14.1 ± 3.3 | 13.9 ± 2.9 |
Data are mean ±SD
Abbreviations: HR = heart rate; MAP = mean arterial pressure; RPP = rate pressure product;