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. 2014 Nov 26;113(4):1165–1174. doi: 10.1152/jn.00614.2014

Fig. 3.

Fig. 3.

Excitation of premotor gastric-related NTS neurons by focal nicotine application. A: focal application of nicotine (arrow; 200 μM, 200-ms duration, 20 psi) induced an increase in mEPSC frequency in a gastric-related NTS neuron. Portions of the trace indicated above lines 1 and 2 are expanded in A1 and A2 to demonstrate the increase in miniature inhibitory postsynaptic current (mIPSC) frequency in the 5 s after nicotine application. B: mean mEPSC frequency for 5-s bins prior to and after nicotine application. Control ACSF contained 2 μM TTX. *Significant difference in frequency vs. the 5 s immediately preceding nicotine application (P < 0.05). Inset: example of recording targeted to a PRV614-labeled NTS neuron; arrow indicates the recorded cell, and arrowhead indicates the recording pipette.