Table 1.

Electrical characteristics of existing patch-clamp amplifiers

Parameter	Axopatch 200B or Axoclamp 900A (Molecular Devices)	Weerakoon et al. 2010 and Goldstein et al. 2011	PatchChip
Noise floor for current measurements (voltage clamp)	0.65 pA rms over 5 kHz (high gain)	8 pA rms over 10 kHz	1.1 pA rms over 5 kHz
	1.65 pA rms over 5 kHz (low gain)
Noise floor for voltage measurements (current clamp)	23 μV rms over 10 kHz	150 μV rms over 5 kHz	8.2 μV rms over 10 kHz
Series resistance compensation	0–100 MΩ	0–80 MΩ	0–32 MΩ
Capacitance compensation	0–10 pF	0–10 pF	0–10 pF