Table 3.

Element sequences used in transfection experiment

Species	HRE1 (5′-3')	HRE2 (5′-3′)	ORE (5′-3′)	Accession No.
Human (Homo sapiens)	CTGTGCGCTCCCACGCC	CAGGCCTGTGTGCACGTA	GGACGTTCCCACGC	NG_012180.1
Anole (Anolis carolinensis)	GTTTGCACTCTTTGGCC	CAGGCATGGGCCAACTTG	AGGCTATCACTCGC	NW_003339315.1
Xenopus (Xenopus tropicalis)	ATTTTCGATACCACATA	CGGGTCTCTGGGCAGTAG	GGAGTTGCTCTAAT	NW_003171408.1

The plasmid construct for each element contained 4 tandem repeats of the element followed by a 12-bp sequence containing a MluI restriction site (5′-ACGCGTATCGAT-3′).

HRE, hypoxia-responsive elements; ORE, oxygen-responsive elements.