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PUFA-induced obesity increased end-diastolic volume (EDV) and reduced ejection fraction in PUFA aging mice at days 1 and 5 post-MI. A: EDV. B: end-systolic volume (ESV). C: ejection fraction. Ejection fraction = [(EDV − ESV)/EDV] × 100. D: infarcted wall. n = 3–8 mice/group per time point. Numbers of mice per group are shown in columns. *P < 0.05 vs. the day 0 control group; ¥P < 0.05 vs. the LC young group at the respective day (analyzed by ANOVA).
