Table 2.
Day 0 Control Group |
Day 1 Post-MI Group |
Day 5 Post-MI Group |
|||||||
---|---|---|---|---|---|---|---|---|---|
LC young | LC aging | PUFA aging | LC young | LC aging | PUFA aging | LC young | LC aging | PUFA aging | |
n | 9 | 3 | 3 | 9 | 4 | 4 | 8 | 9 | 6 |
LV mass, mg | 90 ± 2 | 101 ± 2 | 88 ± 9 | 104 ± 4 | 104 ± 7 | 102 ± 5* | 108 ± 3* | 114 ± 3* | 122 ± 4* |
Tibia length, mm | 18 ± 0.3 | 17 ± 0.1 | 17 ± 0.1 | 18 ± 0.1 | 17 ± 0.1 | 17 ± 0.7 | 18 ± 0.2 | 18 ± 0.2 | 17 ± 0.2 |
LV mass/tibia length | 5 ± 0.3 | 5 ± 0.1 | 5 ± 0.3 | 5 ± 0.1 | 6 ± 0.3 | 6 ± 0.3 | 6 ± 0.2 | 6 ± 0.1 | 7 ± 0.1*† |
RV mass, mg | 18 ± 1 | 20 ± 3 | 21 ± 3 | 19 ± 1 | 20 ± 2 | 24 ± 1*† | 20 ± 1 | 26 ± 1* | 28 ± 2*† |
RV/BW, mg/g | 0.6 ± 0.3 | 0.6 ± 0.1 | 0.6 ± 0.1 | 0.7 ± 0.1 | 0.6 ± 0.1 | 0.7 ± 0.1 | 0.8 ± 0.01* | 0.9 ± 0.03* | 0.8 ± 0.1* |
Wet lung mass, mg | 140 ± 25 | 157 ± 47 | 204 ± 10 | 160 ± 13 | 174 ± 17 | 204 ± 26*† | 196 ± 13* | 320 ± 30* | 265 ± 26* |
Wet lung mass/BW, mg/g | 5 ± 2 | 5 ± 1 | 6 ± 1 | 5 ± 1 | 6 ± 1 | 6 ± 1 | 8 ± 1* | 11 ± 1* | 8 ± 1* |
Data are means ± SE; n, number of mice/group.
LV, left ventricular; RV, right ventricular; BW, body weight.
P < 0.05 vs. the day 0 control group;
P < 0.05 vs. the LC aging group at the respective time point.