Table 1.
C57BL/10 |
mdx |
|||||
---|---|---|---|---|---|---|
Baseline | Dobutamine (5 μg·kg−1·min−1) | Dobutamine (15 μg·kg−1·min−1) | Baseline | Dobutamine (5 μg·kg−1·min−1) | Dobutamine (15 μg·kg−1·min−1) | |
dP/dtmin-EDV slope | 97.0 ± 6.6* | 152.0 ± 13.6* | 224.6 ± 23.2* | 107.2 ± 6.8* | 133.3 ± 9.03* | 149.7 ± 12.2* |
Tau-EDV slope | −0.013 ± 0.013 | −0.005 ± 0.005 | 0.00006 ± 0.00004 | −0.0002 ± 0.0002 | −0.00003 ± 0.0002 | −0.00003 ± 0.0001 |
Values are mean ± SE; n = 17–19.
EDV, end-diastolic volume.
Data derived from changes in both preload and afterload in the left ventricle.
Significantly different from zero.