Table 1.

Data summarizing the load dependence of measures of diastolic function

	C57BL/10			mdx
	Baseline	Dobutamine (5 μg·kg−1·min−1)	Dobutamine (15 μg·kg−1·min−1)	Baseline	Dobutamine (5 μg·kg−1·min−1)	Dobutamine (15 μg·kg−1·min−1)
dP/dtmin-EDV slope	97.0 ± 6.6*	152.0 ± 13.6*	224.6 ± 23.2*	107.2 ± 6.8*	133.3 ± 9.03*	149.7 ± 12.2*
Tau-EDV slope	−0.013 ± 0.013	−0.005 ± 0.005	0.00006 ± 0.00004	−0.0002 ± 0.0002	−0.00003 ± 0.0002	−0.00003 ± 0.0001

Values are mean ± SE; n = 17–19.

EDV, end-diastolic volume.

Data derived from changes in both preload and afterload in the left ventricle.

^*Significantly different from zero.