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. 2015 Jan 21;5(4):378–398. doi: 10.7150/thno.10084

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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A, laser confocal fluorescence microscopy images of cells (A549, MDA-MB-231 and MCF-7) incubated with different fluorescent probes (MaAbNA, anti-EGFR1 nanobody 7D12 and ZHER2:4 affibody), with or without blocking dose of free MaAbNA. B, mean fluorescence intensity of cells treated with the three fluorescent probes, while MaAbNA-treated cells were compared to the block. C, mean fluorescence intensity of cells treated with anti-EGFR1 nanobody 7D12 and ZHER2:4 affibody probes, compared to the blocking by free MaAbNA. Data are given as mean±SD (n=5). *P <0.05.