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. 2015 Feb 1;5(4):399–417. doi: 10.7150/thno.10351

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Evaluation of cell membrane permeability and viability. (A) Effect on HUVEC membrane permeability after blasting with NMB, CMB or CMB105. White arrows represent cells with increased membrane permeability, purple arrows represent cells with no change in the permeability, and blue arrows represent dead cells. (B) The percentage of cells with increased membrane permeability was highest after treatment using ultrasound with CMB105 (^*P<0.01 compared with control, NMB and CMB). n=3 per group. (C) MTT analysis of cell viability. After ultrasound with CMB or CMB105, the cell viability decreased (^*P<0.01 compared with control, NMB and CMB groups, ^**P<0.01 compared with control, NMB and CMB105, ^#P>0.05 compared with control). n=3 per group.