Table 2. Expression level of enzymes related to carbohydrate metabolism.
Relative expression | ||||
---|---|---|---|---|
Mammalian metabolic enzymes of following | C. elegans genes | control | exposure | Sig. |
Hexokinase | C50D2.7 | 1.03 ± 0.13 | 0.89 ± 0.12 | - |
Phosphoglucose isomerase | gpi-1 | 1.00 ± 0.10 | 0.90 ± 0.08 | - |
Phosphofructokinase | fbp-1 | 1.00 ± 0.04 | 0.99 ± 0.11 | - |
Aldolase | aldo-1 | 1.01 ± 0.08 | 0.95 ± 0.06 | - |
aldo-2 | 1.01 ± 0.12 | 1.05 ± 0.15 | - | |
Triose-phosphate isomerase | tpi-1 | 1.01 ± 0.12 | 0.91 ± 0.15 | - |
Fructose bisphosphatase | fbp-1 | 0.99 ± 0.11 | 0.80 ± 0.12 | - |
Glyceraldehyde phosphate dehydrogenase | gpd-1 | 1.00 ± 0.11 | 2.07 ± 0.63 | ** |
gpd-4 | 1.01 ± 0.16 | 1.96 ± 0.54 | ** | |
Phosphoglycerate kinase | pgk-1 | 0.98 ± 0.06 | 0.88 ± 0.09 | - |
Phosphoglycerate mutase | F57B10.3 | 1.00 ± 0.07 | 1.00 ± 0.12 | - |
Enolase | enol-1 | 1.01 ± 0.17 | 0.79 ± 0.16 | - |
Pyruvate kinase | pyk-1 | 1.00 ± 0.07 | 1.05 ± 0.08 | - |
pyk-2 | 1.01 ± 0.13 | 1.03 ± 0.14 | - | |
Pyruvate dehydrogenase A | T05H10.6 | 1.01 ± 0.22 | 0.83 ± 0.14 | - |
Pyruvate dehydrogenase B | C04C3.3 | 0.97 ± 0.06 | 0.83 ± 0.09 | - |
Dihydrolipoamide dehydrogenase | F23B12.5 | 1.01 ± 0.07 | 0.88 ± 0.08 | - |
PEPCK-C | pck-1 | 1.02 ± 0.20 | 0.92 ± 0.27 | - |
Pyruvate carboxylase | pyc-1 | 1.06 ± 0.19 | 1.49 ± 0.48 | - |
The exposure group was treated with 50 Hz, 3 mT ELF-EMF. Value of relative expression is shown in the form of mean fold change ± SEM. ** represents P < 0.01, with respect to the control, “-” represents “no significant in statistics”. Each experiment was repeated six times independently.