Figure 1. Participant-reported hot flush symptoms during 30 minute intravenous infusion of neurokinin B (Study 1).

Five healthy women were monitored for 180 minutes in a Clinical Research Unit. They were administered an intravenous infusion of neurokinin B (NKB, 5.12 nmol/kg/h) between 90–120 minutes. Red ovals represent timings and duration of participant-reported hot flush symptoms. Hot flush symptoms were reported by four out of five participants.