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. 2014 Nov 24;6(2):168–172. doi: 10.1021/ml500423v

Table 2. Receptor-Binding Affinities (IC50) of Reference Peptides and FIB Conjugates.

compd MC1 receptor IC50 (pM)a αvβ3 receptor IC50 (nM)b
[125I]NDP-MSH 71 ± 4  
FIB-NDP-MSH 21 ± 1  
[125I]echistatin   1.40 ± 0.01
FIB-PRGD2   1.10 ± 0.60
a

B16F10 murine melanoma cells.

b

U87-MG human glioblastoma cells.