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. 2014 Nov 24;6(2):168–172. doi: 10.1021/ml500423v

Table 3. PET Quantitative Analysis of Tumors and Selected Tissues at 1 and 3 h after i.v. Injection of Radiotracer in Mice.

compd time tumord muscled boned TMRe
[18F]9a 1 h 6.8 ± 1.9 1.1 ± 0.6 0.9 ± 0.1 6.5 ± 2.4
3 h 6.9 ± 0.5 0.4 ± 0.1 0.5 ± 0.1 15.5 ± 1.5
[18F]FIB-NDP-MSHb 1 h 1.4 ± 0.9 0.3 ± 0.2 0.4 ± 0.2 4.0 ± 0.8
3 h 0.7 ± 0.2 0.1 ± 0.0 0.2 ± 0.1 4.3 ± 1.2
[18F]FIB-PRGD2c 1 h 7.3 ± 1.0 1.6 ± 0.7 1.7 ± 0.8 5.3 ± 2.5
3 h 4.3 ± 1.0 0.9 ± 0.2 1.5 ± 0.9 4.9 ± 0.1
a

B16F0 primary melanoma-bearing C57BL/6J mice.

b

B16F10 primary melanoma-bearing C57BL/6J mice.

c

U87-MG primary glioblastoma-bearing nude mice.

d

Data are expressed as percentage of injected dose per gram of tissue (%ID·g–1) ± SD.

e

Tumor-to-muscle ratio.