Table 1.
a. Characteristics of children with invasive H. influenzae, 1999–2008 | ||||||
---|---|---|---|---|---|---|
Age <3 mos (n=216) % |
Age 3–11 mos (n=186) % |
Age 1–4 yrs (n=230) % |
Age 5–17 yrs (n=196) % |
Total (n=828) % |
||
Serotypes | ||||||
Nontypeable | 82.2 | 37.3 | 50.0 | 64.3 | 59.0 | |
Non-b | 6.4 | 43.2 | 34.4 | 20.4 | 25.7 | |
Type b | 3.2 | 11.9 | 7.4 | 5.1 | 6.7 | |
Unknown | 8.2 | 7.6 | 8.3 | 10.2 | 8.6 | |
Syndromes | ||||||
Bacteremia w/o focus | 83.6 | 33.0 | 34.8 | 46.9 | 50.1 | |
Pneumonia | 7.3 | 20.0 | 29.6 | 19.4 | 19.2 | |
Meningitis | 5.9 | 33.5 | 19.1 | 14.3 | 17.7 | |
Other | 3.2 | 13.5 | 16.5 | 19.4 | 13.0 | |
Underlying conditions1 | ||||||
Any condition | 51.2 | 10.6 | 23.2 | 35.3 | 27.3 | |
Asthma | 0 | 3.9 | 11.4 | 12.6 | 6.2 | |
Dialysis | 0 | 0 | 0.5 | 2.1 | 0.5 | |
Heart failure | 0 | 0.6 | 1.4 | 0 | 0.4 | |
Hematologic malig | 0 | 0 | 3.6 | 7.9 | 2.5 | |
HIV/AIDS | 0 | 0.6 | 0 | 4.6 | 1.2 | |
Immunocompromised | 0.5 | 2.2 | 10.0 | 14.2 | 6.0 | |
Nephrotic syndrome | 0 | 0 | 0.5 | 2.6 | 0.7 | |
Non-hematologic malig | 0 | 0 | 2.3 | 2.6 | 1.1 | |
Prematurity | 49.8 | 2.8 | 1.4 | 0 | 12.7 | |
Hospitalization | 94.1 | 80.5 | 78.3 | 74.0 | 81.9 | |
Healthcare-associated HI | 4.6 | 6.5 | 8.7 | 6.6 | 6.6 | |
Length of stay in days, median (IQR) | 11 (7–30) | 8 (4–14) | 6 (3–11) | 4 (3–9) | 8 (3–15) | |
In-hospital Mortality | 16.2 | 6.5 | 4.4 | 5.6 | 8.3 |
b. Characteristics of adults with invasive H. influenzae, 1999–2008 | |||||
---|---|---|---|---|---|
Age 18–39 yrs (n=485) % |
Age 40–64 yrs (n=1341) % |
Age ≥ 65 yrs (n=2185) % |
Total (n=4011) % |
||
Serotypes | |||||
Nontypeable | 60.8 | 53.3 | 64.8 | 60.5 | |
Non-b | 19.0 | 28.2 | 20.3 | 22.8 | |
Type b | 2.3 | 3.4 | 1.7 | 2.3 | |
Unknown | 17.9 | 15.2 | 13.1 | 14.4 | |
Syndromes | |||||
Bacteremia w/o focus | 37.7 | 32.1 | 26.5 | 29.7 | |
Pneumonia | 31.3 | 51.2 | 66.2 | 56.9 | |
Meningitis | 9.7 | 6.9 | 2.8 | 5.0 | |
Other | 21.2 | 9.9 | 4.6 | 8.4 | |
Underlying conditions2 | |||||
Any condition | 51.3 | 75.2 | 79.6 | 74.8 | |
Alcohol | 5.9 | 12.5 | 2.8 | 6.4 | |
Asthma | 9.0 | 10.7 | 6.0 | 7.9 | |
ASCVD | 0.4 | 9.1 | 28.7 | 18.8 | |
Cirrhosis | 2.0 | 4.7 | 1.3 | 2.5 | |
COPD | 2.2 | 16.4 | 29.6 | 21.9 | |
CSF leak | 0.9 | 0.6 | 0.1 | 0.4 | |
CVA3 | 0.3 | 3.0 | 7.7 | 4.6 | |
Diabetes | 6.1 | 19.2 | 22.4 | 19.4 | |
Dialysis | 4.4 | 7.3 | 7.9 | 7.3 | |
Heart failure | 1.5 | 7.5 | 25.7 | 16.8 | |
Hematologic malig | 2.2 | 7.2 | 6.8 | 6.4 | |
HIV/AIDS | 13.3 | 7.7 | 0.1 | 4.2 | |
Immunocompromised | 9.0 | 14.9 | 11.3 | 12.2 | |
IVDU | 4.6 | 3.7 | 0 | 1.8 | |
Lupus | 1.8 | 0.8 | 0.4 | 0.7 | |
Nephrotic syndrome | 0.4 | 0.3 | 1.2 | 0.8 | |
Non-hematologic malig | 2.6 | 10.0 | 12.3 | 10.4 | |
Smoker3 | 21.9 | 27.9 | 8.3 | 16.5 | |
Hospitalization | 85.6 | 91.0 | 94.9 | 92.5 | |
Healthcare-associated HI | 7.8 | 7.5 | 5.2 | 6.3 | |
Length of stay in days, median (IQR) | 4 (3–9) | 7 (4–13) | 6 (4–11) | 6 (4–11) | |
In-hospital Mortality | 7.1 | 12.4 | 21.9 | 17.0 |
Information on underlying conditions was available for 215 cases <3 mos, 180 cases 3–11 mos, 220 cases 1–4 yrs, and 190 cases 5–17 yrs. HIV status was not collected in New York State.
Information on underlying conditions was available for 456 cases 18–39 yrs, 1276 cases 40–64 yrs, and 2106 cases ≥65 yrs. HIV status was not recorded in New York State.
Surveillance for smoking status began in 2000 and for CVA in 2001.