Table 1. Splicing regulatory protein binding sites ASSEDA scans for and their associated effect on : splicing.
Splicing Factor | R sequence (bits) | Sequence Logo | Location-dependent effect on splicing | |
---|---|---|---|---|
Intronic | Exonic | |||
hnRNPH1 | 8.9 ± 1.8 | E 79, 80 / S 81, 82 | S / E 83 | |
hnRNPA1 i | 4.6 ± 1.5 | S / E 84 | S | |
TIA1 | 7.6 ± 3.1 | E | N/A | |
SRSF6 (SRp55) | 5.2 ± 1.4 | E / S 82 | E / S | |
SRSF5 (SRp40) | 4.5 ± 1.5 | E / S 82 | E / S 85 | |
SRSF2 (SC35) | 4.5 ± 1.6 | E / S 86 | E / S 87 | |
SRSF1 (SF2/ASF) 88 | 5.8 ± 1.5 | E / S 86, 89, 90 | E / S | |
PTB ii | 4.9 ± 1.9 | S / E 91 | S | |
ELAV1 | 9.6 ± 3.4 | S / E / N 92, 93 | S |