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. 2014 Oct 5;16(10):e16433. doi: 10.5812/ircmj.16433

Table 3. Effect of Coenzyme Q10 on Serum Lipoproteins and Plasma Fibrinogen Concentration in the Study Groupsa,b,c.

Coenzyme Q10 P Valued Placebo P Valued P Valuee
Week 0 Week 12 Week 0 Week 12
TC, mmol/L 5.69 ± 0.57 4.47 ± 0.33 < 0.001 5.67 ± 0.59 4.93 ± 0.57 < 0.001 0.231
LDL-C, mmol/L 3.46 ± 0.34 2.70 ± 0.31 < 0.001 3.47 ± 0.34 2.70 ± 0.35 < 0.001 0.56
HDL-C, mmol/L 1.15 ± 0.17 1.44 ± 0.18 < 0.001 1.15 ± 0.18 1.14 ± 0.18 0.812 < 0.001
TG, mmol/L 2.39 ± 1.05 2.48 ± 0.12 0.324 2.23 ± 1.07 2.25 ± 0.69 0.341 0.145
Fibrinogen, g/L 3.88 ± 1.05 2.08 ± 0.99 0.001 3.99 ± 0.88 3.87 ± 0.64 0.451 0.301

a Abbreviations: TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; and TG, triglyceride.

b Values are means ± 2SD.

c P value < 0.05 was considered as statistically significant.

d P Value for the comparison of changes within group (paired-sample t test).

e P Value for the comparison of changes between groups (ANCOVA).