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. Author manuscript; available in PMC: 2015 Feb 16.
Published in final edited form as: Transpl Int. 2007 Mar 16;20(6):534–541. doi: 10.1111/j.1432-2277.2007.00470.x

Figure 1.

Figure 1

TRegs powerfully prevent the rejection of minor histocompatibility mismatched skin allografts. (a) 4 × 105 TRegs adoptively transferred into syngeneic Rag−/− Balb/c hosts together with 4 × 105 CD4+CD25− T cells show a greater capacity to delay the acute rejection of minor histocompatibility mismatched (B10.D2; H-2d) than that of MHC-mismatched (C57BL/6; H-2b) skin allografts (P < 0.0039). (b) The transfer of 4 × 105 CD4+CD25− T cells results in more rapid acute rejection of C57BL/6 than B10.D2 allografts (P < 0.0499). MST, median survival time in days.