Table 2.
Zone of inhibition (mm) of the synthesized compounds.
| Compounds | Zone of inhibition (mm)# | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Gram positive bacteria | Gram negative bacteria | Fungal strains | ||||||||
| B. subtilis | B. cereus | S. epidermidis | S. aureus | E. coli | K. pneumoniae | P. mirabilis | P. aeruginosa | C. albicans | C. tropicalis | |
| 4a | 18.6 | 16.5 | — | 14.0 | 16.0 | — | — | 11.8 | — | 16.0 |
| 4b | — | — | 12.8 | — | — | 11.0 | — | — | — | — |
| 4c | — | 14.6 | — | 16.8 | — | 18.4 | 18.4 | 17.8 | 21.8 | 19.4 |
| 4d | 22.4 | 19.6 | 17.4 | 20.2 | 10.4 | — | — | — | — | — |
| 4e | — | — | 14.5 | — | — | 15.4 | 16.0 | — | — | — |
| 4f | — | — | — | 14.8 | 14.8 | — | — | — | — | |
| 4g | 15.3 | 18.4 | — | — | 20.0 | 17.0 | 17.6 | 18.2 | 22.2 | 14.8 |
| 4h | 24.3 | 20.8 | 19.6 | 22.4 | 15.6 | 14.0 | — | 15.0 | 17.0 | 15.0 |
| 4i | — | 15.4 | — | 13.5 | — | 12.0 | — | — | — | |
| 4j | — | 18.1 | 12.4 | — | 19.2 | — | 16.8 | — | 11.6 | 18.0 |
| 4k | 11.6 | — | 10.6 | — | 20.6 | 19.6 | 17.4 | 18.8 | — | — |
| 4l | — | — | 11.0 | — | — | 9.8 | 10.2 | — | 10.8 | — |
| 4m | — | 17.0 | — | 18.0 | 20.0 | — | 12.0 | — | — | — |
| 4n | 18.8 | 17.4 | 20.4 | 19.6 | 22.8 | 20.0 | 18.2 | 20.1 | — | 21.4 |
| 4o | — | 11.4 | — | — | 13.0 | — | 11.2 | — | — | 10.2 |
| Ciprofloxacin | 25.4 | 23.5 | 21.0 | 26.0 | 25.0 | 24.7 | 20.2 | 21.0 | NT | NT |
| Fluconazole | NT | NT | NT | NT | NT | NT | NT | NT | 25.0 | 24.6 |
#Average of three determinations; NT: not tested; — indicates no inhibition.