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. 2015 Feb 16;5:8486. doi: 10.1038/srep08486

Figure 5. The change in behaviour and morphology in rats with cSCI after in vivo lentiviral TNF-α inference.

Figure 5

(A) The BBB scores in the TNF-α-RNAi-LV group are significantly higher than vector group at 5 dpo, 7 dpo and 14 dpo. (B) The expression of PRDX6 mRNA is significantly up-regulated compared to vector group at 7 dpo. (C) Immunohistochemistry shows PRDX6-positive cells are located in the cytoplasm of neurons and glial cells. The PRDX6-positive cells are observed at 3 dpo, 7 dpo and 28 dpo. (D) The number of PRDX6-positive cells is significantly increased at 3 dpo and 7 dpo compared to vector group. Magnitude:40 × 10 μm. Values are expressed in mean ± SED. * p < 0.05 vs. vector group.