Table 1.
Effect of simvastatin on serum lipid profile.
| Treatment | Total cholesterol | Triglycerides | LDL | HDL |
|---|---|---|---|---|
| (mg/dL) | (mg/dL) | (mg/dL) | (mg/dL) | |
| Normal control | 68.63 ± 2.77 | 66.67 ± 1.93 | 21.15 ± 2.27 | 43.03 ± 1.10 |
| Vehicle control | 62.25 ± 4.36 | 65.21 ± 3.36 | 19.95 ± 2.19 | 44.65 ± 1.48 |
| AlCl3 | 90.19 ± 3.22* | 110.9 ± 9.85* | 31.81 ± 2.78* | 30.19 ± 0.98* |
| AlCl3 + rivastigmine | 72.91 ± 3.99 | 72.45 ± 7.58 | 22.21 ± 3.17 | 31.68 ± 2.00 |
| AlCl3 + simvastatin | 55.12 ± 3.54# | 60.81 ± 2.04# | 11.76 ± 2.37# | 42.12 ± 3.27# |
Effect of AlCl3 and AlCl3 + treatments on (a) total cholesterol, (b) triglycerides, (c) LDL, and (d) HDL. Data are presented as mean ± SEM (n = 8). * P < 0.05 as compared to control group and # P < 0.05 as compared to AlCl3 treated group.