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. 2015 Feb 16;7:7. doi: 10.3389/fnagi.2015.00007

Figure 3.

Figure 3

Evaluation of hearing. (A) Evolution of threshold of click-evoked ABR. Control non-exposed mice (n = 12) maintained normal hearing thresholds along the study, with statistically significant differences (p < 0.001, ***) compared to noise damaged mice. Two days after noise insult, a notable TS occurred in exposed animals; at longer post-exposure periods, mice exposed to 120 VS2–20 (n = 7) showed significantly higher values compared to those exposed to 105 VS2–20 (n = 11, p < 0.05, &) and 105 VS9–13 (n = 12, p < 0.01, ##). (B) DPOAE thresholds at individual frequencies at the end of the experiment. 28 days after noise exposure (105 VS2–20, n = 5; 105 VS9–13, n = 8; 120 VS2–20, n = 4) mice showed significant (p < 0.001, ***) higher DPOAE thresholds for all the frequencies as compared to control mice (n = 6). No significant differences were found among exposed animals. VS, violet swept-sine noise; superscripts indicate the noise frequency range (in kHz); the coefficient indicates the noise level in dB SPL.