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. 2015 Jan 31;2015:251521. doi: 10.1155/2015/251521

Table 5.

Adverse events resulting in discontinuation of treatment.

Treatment group Gender Adverse events
Diclofenac F Nausea
F Diarrhea
F Acute leukocytosis
F Eczema
F Stomach pain
M Edema

Wobenzym F Heartburn
M Stomach pain
M Back pain
M Stomach pain accompanied by gastroesophageal reflux and nausea

Placebo F Nausea
F Nausea
F Edema of legs
M Flatulence and diarrhea
M Abnormal laboratory results
M Stomach pain and episodes of vertigo