Table 2.

Univariable metabolic and cardiovascular risk associated with SGA exposure at one year

Outcome: claims diagnosis	Hazard ratio (95% CI) for SGA users vs. AD users	Chi square	p
Essential hypertension	1.27 (1.23-1.31)	208.1066	<0.0001
Diabetes mellitus	1.73 (1.63-1.83)	335.1633	<0.0001
Obesity	1.24 (1.18-1.32)	56.1796	<0.0001
Stroke	2.12 (1.83-2.45)	99.5837	<0.0001
Hypertensive heart disease	1.56 (1.33-1.84)	28.9700	<0.0001
Myocardial infarction	1.40 (1.13-1.72)	9.8147	0.0017
Angina	1.32 (1.15-1.51)	15.4601	<0.0001
Coronary artery disease	1.52 (1.39-1.67)	82.8166	<0.0001
Transient ischemic attack	1.70 (1.48-1.95)	57.3919	<0.0001
Hyperlipidemia	1.28 (1.24-1.33)	175.9416	<0.0001

SGA – second-generation antipsychotic, AD – antidepressant