Table 1.
Secretions induced by fatty acids in taste bud cells and in enteroendocrine cells (EEC) and the membrane FA receptors involved. Circumvallate refers to the circumvallate papillae, Duod/Jejun refers to Duodenum/Jejunum.
| Peptide | Primary site | Fat ligand | FA Receptor | |
|---|---|---|---|---|
| Taste Cells | ||||
| GLP-1 | Circumvallate | LCFA | GPR120 | |
| Serotonin | Circumvallate | LCFA | CD36 | |
| EE Cells | ||||
| K cells | GIP | Duod/Jejun | LCFA | GPR40, 119, 120 |
| S cells | Secretin | Duod/Jejun | LCFA | CD36 |
| I cells | CCK | Duod/Jejun | LCFA | CD36, GPR40 |
| L cells | PYY | Ileum/colon | ShFA | GPR41, 43 |
| L cells | GLP-1 | Ileum/colon | LCFA, OEA | GPR40, 119, 120 |