Table 4. Criteria for Diagnosis of Gorham's Disease.

Variables
1) Positive biopsy for angiomatous tissue
2) Absence of cellular atypia
3) Minimal or no osteoblastic response and absence of dystrophic calcification
4) Evidence of local and progressive osseous resorption
5) Non-expansile, nonulcerative lesion
6) Absence of visceral involvement
7) Osteolytic radiographic pattern
8) Negative hereditary, metabolic, neoplastic, immunologic or infectious etiology
9) Spread to adjacent soft tissue
10) Development of fibrous tissue