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. 2015 Feb 13;56(2):1129–1140. doi: 10.1167/iovs.14-15950

Figure 3.

Figure 3

In vivo retinal imaging. Spectral-domain OCT images taken across the fundus and modified thickness maps derived using MATLAB software at 3 and 6 months post sensitization. Top panel shows representative cross sectional images of the retina at 3 and 6 MPI and the corresponding 3D thickness maps of the mCherry-controls ([A–D]; n = 11 and 10). Middle panel shows representative SD-OCT images and corresponding 3D thickness maps of EAE-mCherry mice ([E–H]; n = 9 and 8). Bottom panel shows representative SD-OCT images and corresponding 3D thickness maps of EAE-NDUFA6Flag mice ([I–L]; n = 14 and 11). A bar plot of the inner retinal thickness at 3 and 6 MPI of all three groups (M). Marked region in OCT images with red lines: RNFL/GCL/IPL, retinal nerve fiber layer/ganglion cell layer/inner plexiform layer. One-way ANOVA followed by Tukey's multiple comparisons test; P < 0.05 considered significant. ***P = 0.001–0.009; ****P = 0.0001–0.0009.