Table 1.
Characteristic | Study Group
|
Group Comparison
|
|||
---|---|---|---|---|---|
Suicide Nonattempters (n = 62) | Suicide Attempters (n = 29) | Test Statistic | P Value | ||
Age, y | 40.4 (12.4) | 34.6 (12.3) | t89 = 2.11 | .04 | |
| |||||
Educational level, y | 14.9 (3.2) | 14.1 (4.3) | t89 = 1.03 | .31 | |
| |||||
HDRS-24 score | 25.7 (6.7) | 27.6 (6.1) | t89 = −1.29 | .20 | |
| |||||
Beck Depression Inventory score | 26.8 (9.6) | 30.7 (10.4) | t87 = −1.73 | .09 | |
| |||||
Beck SSI score | 3.4 (5.5) | 9.7 (11.6) | t89 = −3.52 | .001 | |
| |||||
Beck Suicide Intent Scale score | NA | 14.4 (5.0) | |||
| |||||
Lethality of attempt score | NA | 1.6 (1.7) | |||
| |||||
Lifetime aggression scoreb | 18.2 (4.9) | 19.2 (5.1) | t75 = −0.83 | .41 | |
| |||||
Global Assessment Scale score | 54.0 (10.6) | 48.0 (10.9) | t89 = 2.52 | .01 | |
| |||||
Reasons for Living Scale score | 2.2 (2.4) | 1.6 (1.9) | t89 = 1.03 | .30 | |
| |||||
Beck Hopelessness Scale score | 9.9 (6.7) | 13.3 (5.3) | t89 = −2.39 | .02 | |
| |||||
Age at onset of MDE, y | 23.5 (12.1) | 17.9 (10.3) | t89 = 2.17 | .03 | |
| |||||
Female sex, % | 64.5 | 65.5 |
|
.93 | |
| |||||
Cluster B personality disorder, % | 12.2 | 32.0 | Fisher exact test | .06 | |
| |||||
Lifetime history of abuse, % | 56.7 | 60.7 |
|
.72 | |
| |||||
History of abuse before 15 years of age, % | 45.0 | 46.4 |
|
.90 | |
| |||||
SSI score >0 at baseline, %c | 37.1 | 48.3 |
|
.31 | |
| |||||
Specific activity, mCi/nmol | 3.85 (1.80) | 3.55 (1.85) | t89 = 0.72 | .47 | |
| |||||
Injected dose, mCi/kg | 0.09 (0.05) | 0.10 (0.04) | t89 = −0.96 | .34 | |
| |||||
Injected mass, mg/kg | 0.02 (0.01) | 0.03 (0.02) | t89 = −1.69 | .09 | |
| |||||
fP, % | 6.44 (2.26) | 6.21 (2.13) | t89 = 0.45 | .65 | |
| |||||
VT(CWM), mL/cm3 | 0.29 (0.09) | 0.27 (0.10) | t89 = 0.89 | .38 |
Abbreviations: fP, plasma-free fraction; HDRS-24, 24-item version of Hamilton Depression Rating Scale; MDD, major depressive disorder; MDE, major depressive episode; NA, not applicable; SSI, Scale for Suicide Ideation; VT(CWM), volume of distribution in cerebellar white matter.
SI conversion factor: To convert millicuries to millibecquerels, multiply by 3.7 × 1010.
Unless otherwise indicated, data are expressed as mean (SD).
Determined using the Brown-Goodwin Lifetime History of Aggression Scale for 51 nonattempters and 26 attempters.
Indicates some ideation is present at entry into the study.