Table 1.

Description of the 15 individual laser lesions examined in this study. Lesions 1 – 6 in each monkey were made on one occasion, and then lesions 7 – 9 in monkey 1 were placed 16 months later. Power levels ranged from 100 to 260 uW, and durations of laser exposure from 10 to 200 ms, parameters that are common in clinical treatment for diabetic retinopathy or retinal edema. The diameter of the laser beam was set to 200 and 250 μm, but actual initial lesion size estimated from fundus photos ranged from approximately 250 to 420 um.

Lesion	Lesion parameters			Lesion size (μm)
	Diameter	Power	Duration	Energy	Fundus	ONL	ONL
	(μm)	(mW)	(ms)	μW/sec	Image	OCT	Histology
Monkey 1
1	200	260	10	2.6	254	80	57
2	200	200	20	4	329	136	78
3	200	100	100	10	358	112	60
4	200	200	20	4	336	136	95
5	200	100	50	5	291	160	129
6	200	100	50	5	306	176	90
7	250	100	200	20	390		73
8	250	100	100	10	419		279
9	250	100	200	20	375		127
Monkey 2
1	200	200	20	4	314	136	66
2	200	100	100	10	388	181	138
3	200	100	50	5	343	115	116
4	200	200	50	4	261	146	70
5	200	100	200	20	418	284	230
6	200	260	10	2.6	0	0	0