Table 10.

Exploratory Multivariable Cox Proportional Model for Mortality and All Cause Adverse Events (Death, AMI, Stroke, and Amputation)

	Mortality			Adverse Events
	HR	95% CI	P Value	HR	95% CI	P Value
Unadjusted
Female gender	0.93	0.60; 1.44	0.74	0.90	0.63; 1.29	0.57
Adjusted step 1
Female gender	0.90	0.58; 1.39	0.63	0.87	0.61; 1.24	0.43
Age	1.05	1.03; 1.08	<0.001	1.06	1.04; 1.08	<0.001
Adjusted step 2
Female gender	0.86	0.55; 1.34	0.50	0.85	0.59; 1.23	0.39
Age	1.05	1.02; 1.08	<0.001	1.06	1.04; 1.08	<0.001
Diabetes	0.92	0.56; 1.49	0.72	0.98	0.67; 1.45	0.94
Current smoking	1.57	1.00; 2.45	0.048	1.59	1.10; 2.30	0.013
Prior stroke	0.74	0.32; 1.72	0.48	0.95	0.52; 1.75	0.87
Prior AMI	1.30	0.81; 2.10	0.28	1.72	1.18; 2.52	0.005
Heart failure	3.27	1.80; 5.92	<0.001	2.04	1.19; 3.49	0.010
Renal dysfunction	1.90	1.07; 3.39	0.030	1.53	0.93; 2.52	0.10
Adjusted step 3
Female gender	0.72	0.41; 1.25	0.24	0.70	0.45; 1.10	0.12
Age	1.04	1.01; 1.07	0.004	1.06	1.03; 1.08	<0.001
Diabetes	0.90	0.51; 1.58	0.72	0.99	0.63; 1.55	0.96
Current smoking	1.42	0.85; 2.36	0.18	1.54	1.02; 2.33	0.041
Prior stroke	0.93	0.40; 2.20	0.88	1.06	0.56; 2.02	0.85
Prior AMI	1.22	0.69; 2.15	0.50	1.56	1.01; 2.43	0.047
Heart failure	2.76	1.36; 5.58	0.005	1.77	0.95; 3.32	0.07
Renal dysfunction	2.03	1.06; 3.88	0.034	1.58	0.90; 2.77	0.11
No partner	1.67	0.97; 2.87	0.06	1.55	0.90; 2.77	0.050
Lower education	1.12	0.66; 1.88	0.68	0.96	0.63; 1.47	0.86
Depression	1.60	0.97; 2.63	0.06	1.60	1.06; 2.41	0.026

Hazard ratios (HR) and 95% CIs are presented. AMI indicates acute myocardial infarction.