Table 5.
Odds Ratios (OR) for Clinical Outcomes by Standard Care With IV Thrombolysis Compared to Without IV Thrombolysis After Excluding Patients Who Received the Low‐Dose tPA (0.6 mg/kg)
| mRS Score of 0 to 1 at 3 Months | Symptomatic HT* | Death at 3 Months* | |||||||
|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | P Value | OR* | 95% CI | P Value | OR* | 95% CI | P Value | |
| Crude analysis | 0.88 | 0.60 to 1.31 | 0.53 | 7.08 | 1.69 to 28.24 | 0.007 | 0.72 | 0.08 to 2.94 | 0.97 |
| PS matching* | 1.81 | 1.06 to 3.08 | 0.03 | 6.14 | 0.93 to Infinity | 0.116 | 0.31 | 0.01 to 2.82 | 0.50 |
| PS matching with additional adjustments* | 2.00 | 1.14 to 3.51 | 0.016 | 3.79 | 0.48 to Infinity | 0.29 | 0.48 | 0.01 to 5.03 | 0.89 |
PS‐matched sample included 117 pairs with 1:1 in 50 pairs and 1:2 in 67 pairs. HT indicates hemorrhagic transformation; IV, intravenous; mRS, modified Rankin disability scale; NIHSS, National Institutes of Health Stroke Scale; PS, propensity score; tPA, tissue plasminogen activator.
For the symptomatic HT and 3‐month mortality, exact logistic regression analyses were performed.
Adjusted for age, sex, baseline NIHSS score, and onset to arrival time.
Adjusted for age, NIHSS, and total cholesterol.