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. 2015 Jan 9;4(1):e001306. doi: 10.1161/JAHA.114.001306

Table 5.

Odds Ratios (OR) for Clinical Outcomes by Standard Care With IV Thrombolysis Compared to Without IV Thrombolysis After Excluding Patients Who Received the Low‐Dose tPA (0.6 mg/kg)

mRS Score of 0 to 1 at 3 Months Symptomatic HT* Death at 3 Months*
OR 95% CI P Value OR* 95% CI P Value OR* 95% CI P Value
Crude analysis 0.88 0.60 to 1.31 0.53 7.08 1.69 to 28.24 0.007 0.72 0.08 to 2.94 0.97
PS matching* 1.81 1.06 to 3.08 0.03 6.14 0.93 to Infinity 0.116 0.31 0.01 to 2.82 0.50
PS matching with additional adjustments* 2.00 1.14 to 3.51 0.016 3.79 0.48 to Infinity 0.29 0.48 0.01 to 5.03 0.89

PS‐matched sample included 117 pairs with 1:1 in 50 pairs and 1:2 in 67 pairs. HT indicates hemorrhagic transformation; IV, intravenous; mRS, modified Rankin disability scale; NIHSS, National Institutes of Health Stroke Scale; PS, propensity score; tPA, tissue plasminogen activator.

*

For the symptomatic HT and 3‐month mortality, exact logistic regression analyses were performed.

*

Adjusted for age, sex, baseline NIHSS score, and onset to arrival time.

*

Adjusted for age, NIHSS, and total cholesterol.