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. 2015 Jan 27;4(1):e001423. doi: 10.1161/JAHA.114.001423

Table 9.

Correlation Between Mean Blood TLR2 Methylation and Plasma Inflammatory Markers

TLR2 Methylation
Position 1 Position 2 Position 3 Position 4 Position 5
Correlation Coefficient P Value* Correlation Coefficient P Value* Correlation Coefficient P Value* Correlation Coefficient P Value* Correlation Coefficient P Value*
IL‐6 −0.067 0.08 −0.025 0.52 0.067 0.08 0.040 0.30 0.020 0.60
IL‐8 −0.004 0.93 0.006 0.88 0.095 0.01 0.053 0.17 0.049 0.20
IL‐1β −0.031 0.42 0.040 0.31 0.046 0.23 0.019 0.63 0.015 0.70
TNF‐α −0.043 0.27 −0.056 0.15 0.006 0.87 −0.009 0.81 −0.039 0.32
TNFγ −0.030 0.44 −0.007 0.86 −0.017 0.66 −0.029 0.45 −0.022 0.58
CRP 0.032 0.35 −0.007 0.85 0.011 0.76 0.024 0.49 0.047 0.17
ICAM‐1 0.138 <0.0001 0.159 <0.0001 0.127 0.0002 0.123 0.0004 0.124 0.0003
VEGF −0.022 0.57 −0.016 0.68 0.091 0.02 0.050 0.20 0.046 0.24

CRP indicates C‐reactive protein; ICAM‐1, intercellular adhesion molecule 1; IL, interleukin; TLR2, Toll‐like receptor 2; TNF, tumor necrosis factor; VEGF, vascular endothelial growth factor.

*

P value represents Prob>|r| under H0: ρ (Spearman's rank correlation coefficient)=0.