Table 1.
Baseline and mid‐term Clinical and Laboratory Characteristics of Persistent Apparently Healed Vs Nonpersistently Apparently Healed Patients
| Persistently Apparently Healed Patients (n=38) | Nonpersistently Apparently Healed Patients (n=21) | P Value | |
|---|---|---|---|
| Parameters at baseline | |||
| Age at diagnosis, y | 42±13 | 42±3 | 0.940 |
| Male, % | 74 | 81 | 0.401 |
| Familial DCM, % | 16 | 24 | 0.449 |
| Duration of HF, months | 5±11 | 9±17 | 0.20 |
| SBP, mm Hg | 127±14 | 132±16 | 0.215 |
| Heart rate, beats/min | 80±18 | 77±12 | 0.442 |
| NYHA classes III to IV, % | 24 | 19 | 0.681 |
| Serum Hb, g/dL | 14.0±1.6 | 14.6±1.6 | 0.286 |
| Serum creatinine, mg/dL | 1.10±0.19 | 1.13±0.17 | 0.700 |
| Sinus rhythm, % | 90 | 100 | 0.133 |
| LBBB, % | 13 | 25 | 0.256 |
| LAAI, cm2/m2 | 12±4 | 12±4 | 0.580 |
| LVEF, % | 36±10 | 36±13 | 0.901 |
| LVEDDI, mm/m2 | 33±4 | 33±4 | 0.957 |
| LVEDVI, mL/m2 | 84±27 | 94±39 | 0.308 |
| RFP, % | 18 | 30 | 0.315 |
| Significant MR, % | 17 | 45 | 0.022 |
| β‐blockers after first evaluation, % | 84 | 86 | 0.878 |
| ACEi/ARBs after first evaluation, % | 82 | 95 | 0.142 |
| Parameters at mid‐term follow‐up | |||
| SBP, mm Hg | 127±14 | 126±9 | 0.775 |
| Heart rate, beats/min | 64±9 | 66±9 | 0.562 |
| NYHA class II (vs NYHA class I), % | 23 | 18 | 0.666 |
| Serum Hb, g/dL | 13.0±1.7 | 15.3±0.5 | 0.52 |
| Sinus rhythm, % | 94 | 94 | 1.00 |
| LBBB, % | 11 | 11 | 1.00 |
| LAAI, cm2/m2 | 11±3 | 11±2 | 0.725 |
| LVEF, % | 53±3 | 54±4 | 0.649 |
| LVEDDI, mm/m2 | 29±4 | 28±3 | 0.755 |
| LVEDVI, mL/m2 | 61±14 | 66±18 | 0.277 |
| RFP, % | 0 | 6 | 0.153 |
| Significant MR, % | 0 | 6 | 0.147 |
| β‐blockers after midterm evaluation, % | 82 | 81 | 0.953 |
| ACEi/ARBs after midterm evaluation, % | 90 | 90 | 0.908 |
ACEi indicates angiotensin‐converting enzyme inhibitors; ARBs, angiotensin receptor blockers; Hb, haemoglobin; HF, heart failure; LAAI, indexed left atrial area; LBBB, left bundle‐branch block; LVEDDI, indexed left ventricular end‐diastolic diameter; LVEDVI, indexed left ventricular end‐diastolic volume; LVEF, left ventricular ejection fraction; MR, mitral regurgitation; NYHA, New York Heart Association; RFP, restrictive filling pattern; SBP, systolic blood pressure.