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Iron oxide nanoparticle based plasma glucose regulation triggered by radio-wave heating: (A) Schematic illustration of cell activation and gene expression induced by iron oxide nanoparticle. (B) Effects of RF treatment on blood glucose (i) and plasma insulin (ii) in PBS and nanoparticle-treated mice with tumors expressing TRPV1His and calcium-dependent human insulin. Adapted with permission from Ref. [92].
