Table 4.

Final Multivariate Model

Variable	Hazard Ratio	95% C.I.	p value
Female gender	0.87	0.44 – 1.71	0.69
Age at presentation	1.00	0.98 – 1.02	0.89
Race (Non-Caucasian vs. Caucasain)	1.54	0.74 – 3.21	0.25
Graves’ disease	3.00	0.33 – 27.54	0.33
Toxic multinodular goiter	0.51	0.06 – 4.38	0.54
# co-morbidities	0.91	0.77 – 1.06	0.23
Diabetes	0.43	0.10 – 1.90	0.27
Heart rate	1.02	1.00 – 1.03	0.04
Goiter on exam	0.94	0.54 – 1.63	0.82
Uptake %	1.03	1.01 – 1.05	<0.01
TSH ≤ 0.01 uIU/mL	2.05	1.00 – 4.18	0.05
T3 > 8 pg/mL	0.91	0.53 – 1.58	0.74
Free T4 > 5 ng/dL	2.08	1.20 – 3.62	0.01
RAI dose < 13 mCi	2.97	1.34 – 6.55	<0.01
Methimazole	2.55	1.22 – 5.33	0.01
>1 anti-thyroid medication	1.18	0.57 – 2.45	0.65

Significant items are indicated in bold type.

TSH, thyroid stimulating hormone, RAI, radioactive iodine, IU, international units, mL, milliliters, pg, picograms, ng, nanograms, dL, deciliters, mCi, milli-Curies