Figure 3. Quantification of time courses and amplitudes of responses of pial arteries and veins to locomotion using a linear model reveals distinct dynamics.
(A) Fitted time constants (τD) of vessel recovery from dilation were significantly smaller for arteries (red) than for veins (blue) (ANOVA: p<0.001). Red and blue arrowheads indicate the mean of for arteries (5.5 ± 5.1 s) and veins (25.1 ± 17.9 s), respectively. (B) Values of integrated areas of the estimated impulse response showed larger arterial (5.57 ± 3.93 s−1, red) than venous (2.61 ± 2.01 s−1, blue) diameter changes (ANOVA: p<0.001). (C) Correlation coefficients (cc) between the data and model fitting for arteries (0.62 ± 0.16) and veins (0.52 ± 0.16) were similar across vessel diameters. Data from a total of 151 arteries and 104 veins were included in each plot.