Table 3.
Factors associated with hazardous alcohol use† over follow-up among HIV-infected men who have sex with men, 2002–2011 (n= 1,065).
Characteristics | OR | 95% CI | p-value | AOR | 95%CI | p-value |
---|---|---|---|---|---|---|
Time (per year) | 0.95 | 0.93 – 0.97 | <0.001 | 0.85 | 0.76 – 0.95 | 0.006 |
Time2 (per year2) | - | - | - | 1.02 | 1.00 – 1.03 | 0.024 |
Sociodemographic and Behavioral Characteristics | ||||||
Age at baseline (per 10 years) | 0.81 | 0.73 – 0.90 | <0.001 | 0.92 | 0.80 – 1.05 | 0.219 |
Education (ref: high school or less) | ||||||
Some college or greater | 1.17 | 1.02 – 1.34 | 0.026 | 0.90 | 0.73 – 1.11 | 0.334 |
Race (ref: white) | ||||||
African American | 0.83 | 0.66 – 1.06 | 0.133 | |||
Other | 1.11 | 0.67 – 1.85 | 0.683 | |||
Hispanic/Latino Ethnicity (ref: not H/L) | 1.31 | 0.83 – 2.08 | 0.246 | |||
Marital Status (ref: married, living with partner) | ||||||
Divorced/separated/widowed | 0.95 | 0.69 – 1.31 | 0.756 | |||
Never married | 1.12 | 0.84 – 1.51 | 0.444 | |||
Employment status at baseline (ref: employed) | ||||||
Unemployed/retired/other | 1.01 | 0.81 – 1.26 | 0.935 | |||
Annual income at baseline (ref: ≥$50,000) | ||||||
< $6,000 | 2.43 | 1.57 – 3.76 | <0.001 | 1.74 | 1.08 – 2.79 | 0.022 |
$6,000 – $11,999 | 1.47 | 0.96 – 2.25 | 0.074 | 1.28 | 0.81 – 2.01 | 0.292 |
$12,000 – $24,999 | 1.26 | 0.83 – 1.91 | 0.283 | 1.13 | 0.73 – 1.74 | 0.586 |
$25,000 – $49,999 | 1.34 | 0.88 – 2.04 | 0.170 | 1.27 | 0.83 – 1.96 | 0.272 |
Ever homeless (ref: no) | 1.38 | 1.10 – 1.73 | 0.005 | 0.77 | 0.58 – 1.02 | 0.071 |
Sex partner(s)¶* (ref: males only) | ||||||
Both males and females | 1.17 | 0.90 – 1.52 | 0.231 | |||
Clinical and Substance Use Factors | ||||||
Alcohol-related diagnosis§ (ref: no) | 2.93 | 2.30 – 3.73 | <0.001 | 2.71 | 2.00 – 3.66 | <0.001 |
Drug-related diagnosis§ (ref: no) | 1.41 | 1.16 – 1.70 | <0.001 | 0.86 | 0.68 – 1.09 | 0.216 |
Major depressive disorder diagnosis § (ref: no) | 1.13 | 0.93 – 1.38 | 0.216 | |||
PTSD diagnosis§ (ref: no) | 1.41 | 1.01 – 1.98 | 0.045 | 1.03 | 0.71 – 1.50 | 0.865 |
PHQ-9 score* (per unit increase) | 1.02 | 1.00 – 1.03 | 0.026 | 1.01 | 0.99 – 1.02 | 0.391 |
Cannabis use¶* (ref: no use) | 1.68 | 1.43 – 1.98 | <0.001 | 1.47 | 1.22 – 1.76 | <0.001 |
Cocaine use¶* (ref: no use) | 2.01 | 1.63 – 2.47 | <0.001 | 1.55 | 1.24 – 1.95 | <0.001 |
Stimulant use¶* (ref: no use) | 1.61 | 1.20 −2.17 | 0.002 | 1.17 | 0.85 – 1.61 | 0.334 |
Substance abuse treatment¶* (ref: no) | 1.24 | 1.00 – 1.55 | 0.054 | |||
Positive HCV status at baseline (ref: negative) | 1.22 | 0.97 – 1.54 | 0.087 |
Hazardous alcohol use de ined as ≥ 4 on AUDIT-C (Saitz, 2005);
Denotes use or experiences in the past year;
time-updated variable;
recorded ICD-9 diagnosis between 12 months before VACS enrollment and end of study period.
Abbreviations: AOR = adjusted odds ratio; AUD = alcohol use disorder; DUD = drug use disorder; HCV = hepatitis C virus; PHQ-9 = Patient Health Questionniare-9 (Kroenke et al., 2001); PTSD = posttraumatic stress disorder; OR = odds ratio.