Table 1. Baseline Characteristics.
Data are presented as median (25th percentile–75th percentile) for continuous variables and number (percentage) of patients for categorical variables. N represents the number of non-missing values. Shock on admission was defined as systolic blood pressure <90mmHg or the need for vasopressors or mechanical circulatory support (intra-aortic balloon pump, extracorporeal membrane oxygenation or ventricular assist device) at the time of admission. Index CV SOFA score indicates the score during the achieved MAP.
| Characteristic | N | Overall |
|---|---|---|
| Age (years) | 188 | 59 (50–68) |
| Male (%) | 188 | 118 (63%) |
| Out-of-hospital arrest (%) | 188 | 150 (80%) |
| Initial rhythm VT/VF (%) | 182 | 110 (60%) |
| Witnessed arrest (%) | 188 | 157 (84%) |
| Received bystander CPR (%) | 188 | 98 (52%) |
| Time to ROSC (minutes) | 173 | 18 (12–30) |
| Presence of shock on admission (%) | 188 | 54 (29%) |
| Placement of mechanical circulatory support device (%) | 188 | 32 (17%) |
| Baseline NIMAP (mmHg) | 174 | 84 (76–92) |
| Baseline AMAP (mmHg) | 148 | 86 (81–95) |
| Baseline CV SOFA Score | 174 | 0.09 (0.00–2.60) |
| Achieved NIMAP (mmHg) | 174 | 83.2 (76.4–89.6) |
| Achieved AMAP (mmHg) | 148 | 86 (80–92) |
| Index CV SOFA Score | 174 | 1.73 (0.53–2.71) |
| Initial body temperature (degrees Celsius) | 164 | 36.4 (35.5–36.8) |
| Time from arrest to initiation of TH (minutes) | 177 | 195 (90–320) |
| Time to reach target temperature (minutes) | 171 | 420 (248–550) |
| Time spent at target temperature (hours) | 176 | 19.0 (16.0–23.2) |
| ST-segment Elevation Myocardial Infarction (%) | 187 | 40 (21%) |
| Coronary angiography performed (%) | 188 | 115 (61%) |
| Percutaneous coronary intervention performed (%) | 188 | 62 (33%) |
| Peak Troponin I concentration (mcg/l) | 172 | 4.38 (0.84–20.70) |
| Time from arrest to follow up (months) | 53 | 3.0 (1.0–6.0) |
AMAP = Invasive (Arterial) Mean Arterial Blood Pressure; CPR = Cardiopulmonary Resuscitation; CV SOFA = Cardiovascular Sequential Organ Failure Assessment; NIMAP = Noninvasive Mean Arterial Blood Pressure; ROSC = Return of Spontaneous Circulation; TH = Therapeutic Hypothermia; VT = Ventricular Tachycardia; VF = Ventricular Fibrillation