Table 3. Analysis of haplotype frequency for rs2074192 and rs714205 in female patients.
| Haplotypes rs2074192/rs714205 | DNR n (%) |
Retinopathy |
|||||
|---|---|---|---|---|---|---|---|
|
All DR |
PDR |
NPDR |
|||||
| n (%) | Pa | n (%) | Pb | n (%) | Pc | ||
| C/C | 22 (4.6) | 16 (4.8) | 0.92 | 7 (3.0) | 0.29 | 15 (6.2) | 0.46 |
| C/G | 226 (47.7) | 191 (57.2) | 0.008 | 103 (44.4) | 0.003 | 123 (50.8) | 0.13 |
| T/C | 226 (47.7) | 127 (38.0) | 0.006 | 122 (52.6) | 0.0006 | 104 (43.0) | 0.23 |
Abbreviations: DNR, diabetes without retinopathy; DR, diabetic retinopathy; NPDR, nonproliferative DR; PDR, proliferative DR.
Frequency >0.03 in both DR and DNR groups has been involved to calculate the odds ratio and 95% confidence interval.
P-values <0.05 considered to be statistically significant are shown in bold.
a
P: DNR vs DR.
b
P: DNR vs PDR.
c
P: DNR vs NPDR.