Table 3. Association of smoking and SBP with OCT areas and volumes.
Area CC | Area PR | Volume CC | Volume PR | RA | |
---|---|---|---|---|---|
Smoking status, mean±SD | |||||
Nonsmokers (n=158) | 0.2117±0.0517 | 0.1582±0.0397 | 0.0152±0.0056 | 0.0075±0.0025 | 0.5234±0.1301 |
Smokers (n=50) | 0.1950±0.0862 | 0.1460±0.0614 | 0.0139±0.0094 | 0.0069±0.0035 | 0.3000±0.1372 |
P-valuea | 0.87 | 0.87 | 0.91 | 0.89 | 0.24 |
Years smoked | |||||
≤5 (n=12) | 0.0667±0.0596 | 0.0042±0.0040 | 0.0041±0.0038 | 0.0000±0.0000 | 0.0125±0.0120 |
6–19 (n=13) | 0.4269±0.3052 | 0.1885±0.1488 | 0.0403±0.0347 | 0.0123±0.0110 | 0.1077±0.0995 |
≥20 (n=22) | 0.1545±0.0515 | 0.2159±0.1041 | 0.0055±0.0019 | 0.0083±0.0042 | 0.4705±0.2699 |
P-valuea | 0.32 | 0.06 | 0.59 | 0.08 | 0.15 |
SBP, mm Hg | |||||
<120 (n=68) | 0.0772±0.0258 | 0.0985±0.0396 | 0.0029±0.0010 | 0.0040±0.0017 | 0.3059±0.1389 |
120–139 (n=66) | 0.2250±0.0738 | 0.1568±0.0626 | 0.0136±0.0063 | 0.0082±0.0047 | 0.3614±0.1569 |
≥140 (n=31) | 0.3968±0.1913 | 0.2839±0.1195 | 0.0370±0.0244 | 0.0128±0.0067 | 0.9565±0.3784 |
P-valuea | 0.05 | 0.29 | 0.09 | 0.34 | 0.27 |
Spearman correlation with continuous years smoked, adjusted for age | 0.23, P=0.12 | 0.29, P=0.05 | 0.20, P=0.17 | 0.40, P=0.005 | 0.24, P=0.10 |
Spearman correlation with continuous SBP | 0.06, P=0.42 | 0.18, P=0.01 | 0.08, P=0.26 | 0.18, P=0.02 | 0.15, P=0.05 |
Abbreviations: CC, central circle; OCT, optical coherence tomography; PR, perifoveal ring; RA, retinal pigment epithelium atrophy; SBP, systolic blood pressure.
Generalized estimating equations (GEE).