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. 2015 Jan 27;43(3):1671–1683. doi: 10.1093/nar/gkv023

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© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Synthetic lethality of pold3 and polζ/polη. (A) Western blot for probing existence of POLD3 protein was shown. Protein samples from indicated cells were analyzed. β-actin was analyzed as a loading control. (B) Growth curves of the indicated cells. The transcription of tet-POLD3 was active without doxycycline (−Dox) and inhibited upon addition of doxycycline (+Dox).