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. 2015 Jan 21;43(3):1593–1608. doi: 10.1093/nar/gkv024

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© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Involvement of Oct4-targeted promoter- and enhancer-associated genes in critical signaling pathways relevant to cancer progression. (A and B) Configurations of Oct4 binding (data from Oct4 ChIP-seq), DHS, H3K4me3 and H3K4me1 profiles (data from ENCODE datasets) at promoter-associated (A) and enhancer-associated (B) genes. Snapshots of the binding profiles from Integrative Genomics Viewer. (C and D) Diseases and disorders (upper) and canonical pathways analyses (lower) of promoter-associated (C) and enhancer-associated (D) genes targeted by Oct4 conducted by Ingenuity-IPA.