Table 1. Multivariate Cox regression analysis of risk factors for cancer-related death in lung cancer patients.
| Characteristics | Multivariate analysis | Characteristics | Multivariate analysis | ||
|---|---|---|---|---|---|
| HRa (95% CIb) | P-valuec | HRa (95% CIb) | P-valuec | ||
| Oct4 protein expression | Oct4/PTEN/TNC protein expression | ||||
| Normal expression | 1.00 | Others | 1.00 | ||
| Overexpression | 1.83 (1.00–3.35) | 0.052 | Aberrant expression | 3.24 (1.77–5.94) | <0.001 |
| Age | Age | ||||
| <60 | 1.00 | <60 | 1.00 | ||
| ≥60 | 1.44 (0.75–2.75) | 0.273 | ≥60 | 1.14 (0.59–2.22) | 0.700 |
| Gender | Gender | ||||
| Female | 1.00 | Female | 1.00 | ||
| Male | 1.20 (0.48–3.01) | 0.693 | Male | 1.12 (0.44–2.87) | 0.816 |
| Smoking habit | Smoking habit | ||||
| Non-smoker | 1.00 | Non-smoker | 1.00 | ||
| Smoker | 1.79 (0.80–4.00) | 0.154 | Smoker | 1.67 (0.72–3.84) | 0.230 |
| Tumor typed | Tumor typed | ||||
| SCC | 1.00 | SCC | 1.00 | ||
| ADC | 2.83 (1.34–5.98) | 0.006 | ADC | 1.75 (0.81–3.79) | 0.156 |
| Stage | Stage | ||||
| Stage I-II | 1.00 | Stage I-II | 1.00 | ||
| Stage III-IV | 1.29 (0.55–3.03) | 0.561 | Stage III-IV | 1.95 (0.80–4.77) | 0.144 |
| T stage | T stage | ||||
| Stage 1–2 | 1.00 | Stage 1–2 | 1.00 | ||
| Stage 3–4 | 2.99 (1.49–5.98) | 0.002 | Stage 3–4 | 2.30 (1.15–4.58) | 0.018 |
| N stage | N stage | ||||
| N0 | 1.00 | N0 | 1.00 | ||
| ≥N1 | 3.11 (1.31–7.40) | 0.010 | ≥N1 | 2.17 (0.88–5.37) | 0.093 |
| M stage | M stage | ||||
| M0 | 1.00 | M0 | 1.00 | ||
| ≥M1 | 0.75 (0.26–2.16) | 0.591 | ≥M1 | 0.46 (0.15–1.36) | 0.159 |
aHR, Hazard ratio.
bCI, Confidence interval.
cBold values indicatestatisticalsignificance (P<0.05).
dADC, Adenocarcinoma; SCC, Squamous cell carcinoma.