Table 2.
Control versus alcohol-influenced sleep
| N = 26 | Control sleep Median (IQR) |
Alcohol sleep Median (IQR) |
P value |
|---|---|---|---|
| Sleep architecture | |||
| TST, min | 354.0 (65.3) | 354.0 (62.5) | 0.501 |
| REM % of TST | 25 (8) | 20 (9) | 0.020 |
| NREM % of TST | 75 (8) | 80 (9) | 0.020 |
| WASO, min | 45.7 (74.7) | 40.9 (48.5) | 0.361 |
| Awakenings | 28 (18) | 19 (17) | 0.012 |
| AI | 15.5 (10.0) | 18.6 (10.0) | 0.920 |
| Ventilation | |||
| AHI | 9.7 (10.2) | 10.4 (16.4) | 0.517 |
| HI | 4.8 (6.2) | 6.3 (8.6) | 0.309 |
| ODIa | 5.5 (11.6) | 8.3 (12.8) | 0.548 |
| Mean SpO2 % | |||
| N0 | 94.0 (5.1) | 93.9 (5.6) | 0.551 |
| NREM | 93.7 (4.6) | 93.2 (5.4) | 0.019 |
| REM | 92.5 (5.4) | 92.8 (6.4) | 0.258 |
| Sleep | 93.4 (4.7) | 93.2 (5.7) | 0.058 |
| Mean ΔPtcCO2 kPa | |||
| N0 | 0.19 (0.23) | 0.15 (0.22) | 0.638 |
| NREM | 0.39 (0.34) | 0.55 (0.36) | 0.035 |
| REM | 0.67 (0.46) | 0.67 (0.42) | 0.082 |
| Sleep | 0.49 (0.35) | 0.58 (0.36) | 0.047 |
| Sleep hypoventilation | |||
| SHb | 8 (27) | 19 (40) | 0.179 |
TST total sleep time, REM rapid eye movement sleep, NREM non-REM sleep, WASO wake after sleep onset, Awakenings number of awakenings after sleep onset, AI number of arousals per hour (arousal index), AHI number of apneas/hypopneas per hour (apnea/hypopnea index), HI number of hypopneas per hour (hypopnea index), ODI number of oxygen desaturations per hour (oxygen desaturation index), S p O 2 oxyhemoglobin saturation by pulse oximetry, N0 awake after initial sleep onset, Sleep = NREM + REM, ΔP tc CO 2 carbon dioxide pressure increase from supine, resting value prior to sleep, SH sleep hypoventilation defined by the American Academy of Sleep Medicine as an increase of 1.3 kPa or more in PaCO2 during sleep, to a value exceeding 6.7 kPa for at least 10 min
a N = 25, one missing because of defect finger probe
bPercent of “Yes” within group (SD), instead of median (IQR)s